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MYP_037975
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Basic Information
Polybia-MPI [L14L-S]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
IDWKKLLDAAKQIX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0218593 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=Leu-S
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 20600424 PMID20600424 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20600424/
RECORD: Rec_0237948 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 14
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
16 μM
MIC
PMID20600424 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20600424/
RECORD: Rec_0281431 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=Leu-S
Bio-Activity Profile
Antimicrobial Anticancer
PC-3
20.3±1 μM
IC50
PaperPubMed PMID: 20600424 PMID20600424 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20600424/
RECORD: Rec_0289868 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
X=Leu-S
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 20600424 PMID20600424 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20600424/
RECORD: Rec_0334739 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
unspecified non-canonical residue at 14
Bio-Activity Profile
Anticancer Cytotoxic
Human prostate adenocarcinoma PC-3
20.3
IC50
PMID20600424 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20600424/
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