Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC469H756N122O133S7

DescriptionStandard

        MKLFLVLIILLFEVPADGARLKKCFNNVTGYCRKKCKVGEIYEIGCLSGKLCCVNDEENKKHVPVKKPHTDSGEKPSSHQDYDILPTVTIFTV
    

Molecular Weight10456.21 Da

Isoelectric Point (pI)8.54

Net Charge (pH 7.0)2.71

Net Charge (pH 7.4) 2.22

Charge Density (pH 7.0) 0.0291

GRAVY Index-0.13

Hydrophobic Moment 0.58

Boman Index0.02

Instability Index30.54

Aliphatic Index 93.12

Aromaticity 0.0753

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4087.16

LogP -33.72

H-bond Donors 144.0

H-bond Acceptors 146.0

Rotatable Bonds 352.0

Heavy Atoms 731.0

Ring Count 15.0

Amide Bonds 97.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0034049 VERIFIED: NO

Provenance & Taxonomy

OrganismCallithrix jacchus [Animal]

FamilyDefensin

Tax ID9483

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence