Peptide Database

Peptide NameUnnamed

Function Ontology

Antimicrobial

Cardiovascular

Hormonal / Endocrine ▸ Hormone peptide

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC469H788N146O139S4

DescriptionStandard

        YPLGSPSQSPEQFKMQKLLELIREKSEEMAQRQLLKDQGLTKEHPKRVLRSQGSTLRVQQRPQNSKVTHISSCFGHKIDRIGSVSRLGCNALKLL
    

Molecular Weight10824.43 Da

Isoelectric Point (pI)10.18

Net Charge (pH 7.0)9.01

Net Charge (pH 7.4) 8.60

Charge Density (pH 7.0) 0.0949

GRAVY Index-0.75

Hydrophobic Moment 0.70

Boman Index-0.22

Instability Index68.71

Aliphatic Index 84.11

Aromaticity 0.0316

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4689.12

LogP -52.70

H-bond Donors 164.0

H-bond Acceptors 155.0

Rotatable Bonds 380.0

Heavy Atoms 758.0

Ring Count 11.0

Amide Bonds 106.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0056250 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0140645 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyNatriuretic peptides

Tax ID10090

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide73-89

Bio-Activity Profile

Function

Antimicrobial Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Growth regulation Development regulation Receptor modulation Immunomodulatory

Half-LifeMammalian: 2.8 hour; Yeast: 10 min; E. coli: 2 min

RECORD: Rec_0310005 VERIFIED: NO

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyNatriuretic peptide

Tax ID10090

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide73-89

Bio-Activity Profile

Function

Hormone Cardiovascular