Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length478 amino acids

Chemical FormulaC2458H3824N590O694S21

DescriptionStandard

        MMFLWFVLVLVNLVSVATGTNAGVKVRLTQKGLEYGRQIGIASIQQKLRTIKVPDISGTETVDPIGKVQYSFTGMQIVNLGLPKSALGLVPDTGVMLSIGNGYINLHGNWRVKYLRIIKDSGSFDLAVSELTISTTIAVTNDDTGHPTVSMTNCAATVGSVNVKFHGGASWLYNLFSSFINKALCNALQKQICPLVADSIADINPHLKTLNVLAEVDQYGEFYNIGEHKEPPFSPIPFSFLSQDTDMIYIGVSAFTINSAGFVYNSAGALRLYITDDMTCSVIKLEKTDSKDDLFQIEKMYPGLMMKLLVETVKEPIVTFEPNNMTVQASKMFYNEFPFNQQEGSVSTHIYVTELKLAGNMTLNKIDISLAKSYVGPFQVTSLDNIFTIVLKVAVIPKVNAHLQEGYPLPAIGKMQLVNSRLQVLKVSLCVCVCVYIYIYIYIYIYYYIYIYIYIYIYIYILYIYIYIYTHTYTGASQ
    

Molecular Weight53417.55 Da

Isoelectric Point (pI)6.70

Net Charge (pH 7.0)-0.87

Net Charge (pH 7.4) -1.72

Charge Density (pH 7.0) -0.0018

GRAVY Index0.28

Hydrophobic Moment 0.68

Boman Index0.22

Instability Index22.38

Aliphatic Index 107.80

Aromaticity 0.1192

Extinction Coeff. Reduced 67160.00

Extinction Coeff. Oxidized 67535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0357813 VERIFIED: NO

Provenance & Taxonomy

OrganismCyprinus carpio [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria