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MYP_037837
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Basic Information
D1D6
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antiviral
Antiviral ▸ Anti-Retrovirus ▸ Anti-Lentivirus ▸ Anti-FIV
Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition ▸ Release inhibitor
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
27 amino acids
C137H254N52O28
Standard
Sequence
FLAAARIAKRVAKKARKLAKRAARKRK
Physicochemical Analysis
3077.81 Da
12.00
12.75
12.54
0.4723
-0.70
0.93
-0.53
42.71
87.41
0.0370
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1373.46
-12.30
53.0
41.0
114.0
217.0
1.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0257427 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-FIV Release inhibition
Feline immunodeficiency virus(FIV-Petaluma) | CrFK cells
0.94 μM
IC50
Mammalian: 1.1 h; Yeast: 3 min; E. coli: 2 min
PaperInhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro. | Ma J, Kennedy-Stoskopf S, Jaynes JM, Thurmond LM, Tompkins WA. | J Virol. 2002 Oct;76(19):9952-61. | DOI:10.1128/jvi.76.19.9952-9961.2002 | PMID:12208971 PMID12208971 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12208971/
RECORD: Rec_0264026 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Release inhibitor
Feline immunodeficiency virus (Release); CrFK
0.94 μM
RT-PCR
PaperInhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro. | Ma J, Kennedy-Stoskopf S, Jaynes JM, Thurmond LM, Tompkins WA. | J Virol. 2002 | PMID:12208971 PMID12208971 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12208971/
RECORD: Rec_0300392 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
Feline immunodeficiency virus(FIV-Black):inhibition of reverse transcriptase activity in CrFK cells
1.47 μM
IC50
PaperPubMed PMID: 12208971 PMID12208971 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12208971/
RECORD: Rec_0391834 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
Feline immunodeficiency virus
0.94 μM
IC50
PMID12208971 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12208971/
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