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MYP_037820
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Basic Information
8557
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
12 amino acids
C84H132N20O13S
Standard
Sequence
WKIFKLKLRMLW
Physicochemical Analysis
1662.14 Da
11.26
3.76
3.55
0.3131
0.22
0.54
0.08
4.12
130.00
0.2500
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
554.96
3.01
21.0
18.0
56.0
118.0
5.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0089922 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
C. trachomatis D/UW-3/Cx MIC90 = 50 microM
PMID31302447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31302447/
RECORD: Rec_0186587 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli MG1655
77 μM
MIC
PMID31302447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31302447/
RECORD: Rec_0263094 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human RBC High haemolytic activity, lysing approximately 50% of erythrocytes at concentrations of 6.25 microM
6.25 μM
Hemolysis
PMID31302447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31302447/
RECORD: Rec_0283543 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis 168 HT
38.5 μM
MIC
PMID31302447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31302447/
RECORD: Rec_0361447 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
C. trachomatis D/UW-3/Cx
50 μM
MIC90
PaperMedicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens
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