Peptide Database

Peptide NameConjuagte 3(conjugates of 4-aminocyclophosphamide (4-NH2-CPA))

Function Ontology

Anticancer

Standard StatusStandard

Sequence Length5 amino acids

Chemical FormulaC26H35N7O8

DescriptionStandard

        HYPAS
    

Molecular Weight573.60 Da

Isoelectric Point (pI)6.74

Net Charge (pH 7.0)-0.15

Net Charge (pH 7.4) -0.41

Charge Density (pH 7.0) -0.0307

GRAVY Index-1.02

Hydrophobic Moment 0.12

Boman Index0.08

Instability Index159.08

Aliphatic Index 20.00

Aromaticity 0.2000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 240.07

LogP -2.23

H-bond Donors 8.0

H-bond Acceptors 9.0

Rotatable Bonds 13.0

Heavy Atoms 41.0

Ring Count 3.0

Amide Bonds 4.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006740 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermBn-glutarylation

C-TermAmidation

Bio-Activity Profile

Function

Anticancer

Activity0.00944±0.0003 μM

MethodHPLC

Half-LifeConjuagte 3+PSA(Prostate-specific antigen), in vitro; 3300 s