Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length188 amino acids

Chemical FormulaC928H1486N256O252S9

DescriptionStandard

        PTTPPMAHEPMLLLAVTEFVANSAAFTYFTAGALRRIISSDMVPRRFPLQLSTKSMGIFSPQLQELYPDQPMELHLWARQQPLLSCHADALHGTLLGSAEAFVVLPNATRAPAFLLNIDANVTGKPTITRNRLGGTVRLTGMDPLPALSRAQGLPVPQVKRLETLLKFSLWLFGVPRANSKCCPRAVP
    

Molecular Weight20549.88 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)7.29

Net Charge (pH 7.4) 6.97

Charge Density (pH 7.0) 0.0388

GRAVY Index0.10

Hydrophobic Moment 0.53

Boman Index0.11

Instability Index51.29

Aliphatic Index 96.06

Aromaticity 0.0691

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7964.89

LogP -94.52

H-bond Donors 275.0

H-bond Acceptors 272.0

Rotatable Bonds 649.0

Heavy Atoms 1445.0

Ring Count 39.0

Amide Bonds 201.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0169794 VERIFIED: NO

Provenance & Taxonomy

OrganismMelospiza melodia (Song sparrow) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria