‹ ›
MYP_037787
← PREVIOUS NEXT → BACK
Basic Information
Alyteserin-2Ma
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
16 amino acids
C76H127N19O20
Standard
Sequence
FIGKLISAASGLLSHL
Physicochemical Analysis
1626.94 Da
8.76
0.85
0.59
0.0529
1.27
0.41
0.50
-1.24
158.75
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
615.21
-4.44
22.0
22.0
54.0
115.0
2.0
15.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0197974 VERIFIED: YES
Provenance & Taxonomy
Alytes maurus [Animal]
Alyteserin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus NCTC 10788
9.5 μM
MIC
PMID22800568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22800568/
RECORD: Rec_0223572 VERIFIED: YES
Provenance & Taxonomy
Alytes maurus [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0295401 VERIFIED: YES
Provenance & Taxonomy
Midwife toad [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID22771964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22771964/
RECORD: Rec_0311847 VERIFIED: YES
Provenance & Taxonomy
Alytes maurus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
38.4 μM
MIC
PMID22800568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22800568/
RECORD: Rec_0358680 VERIFIED: YES
Provenance & Taxonomy
Alytes maurus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus NCTC 10788
9.5 μM
MIC
PMID22800568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22800568/
FIRST PREV 1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 3 of 4