Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC447H738N128O121S10

DescriptionStandard

        MKLLYLFLAILLAIEEPVISVECWMDGHCRLLCKDGEDSIIRCRNRKRCCVPSRYLTIQPVTIHGILGWTTPQMSTTAPKMKRNITNR
    

Molecular Weight10162.08 Da

Isoelectric Point (pI)9.27

Net Charge (pH 7.0)5.62

Net Charge (pH 7.4) 5.20

Charge Density (pH 7.0) 0.0639

GRAVY Index0.00

Hydrophobic Moment 0.57

Boman Index0.00

Instability Index74.06

Aliphatic Index 100.80

Aromaticity 0.0568

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4004.85

LogP -33.27

H-bond Donors 148.0

H-bond Acceptors 139.0

Rotatable Bonds 337.0

Heavy Atoms 706.0

Ring Count 14.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0347295 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Animal]

FamilyDefensin

Tax ID61853

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence