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MYP_037755
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Basic Information
Cecropin A-like 4 (3-18)[K2W;G5,12W;E9W;Q13K;H14N;T15W]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C118H172N32O18
Standard
Sequence
LWKIWKKIWRVWKNWR
Physicochemical Analysis
2326.83 Da
12.00
5.76
5.55
0.3598
-0.97
0.95
-0.18
7.08
91.25
0.3125
27500.00
27500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
849.74
2.00
33.0
24.0
74.0
168.0
10.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0046291 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Klebsiella pneumoniae WGLW2
27.5 μM
MIC
PMID33401476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33401476/
RECORD: Rec_0058235 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human hepatocellular carcinoma HepG2
0-10 % Killing
Killing
PMID33401476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33401476/
RECORD: Rec_0107733 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa PA14
13.75 μM
MIC
PMID33401476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33401476/
RECORD: Rec_0144515 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 29231
3.44 μM
MIC
PMID33401476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33401476/
RECORD: Rec_0186379 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
16 μg/mL
HC50
PMID33401476 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/33401476/
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