Peptide Database

Peptide NameTLP1_CASSA

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length243 amino acids

Chemical FormulaC1129H1754N308O349S19

DescriptionStandard

        CPATKYSRIFKQQCPQAYSYAYDDSTSTFTCSGAPDYVITFCPMMKTLALYGLTLALFFLSGAHSAKITFTNNCPRTIWPGTLTSDQKPQLPNNGNGAIPPASLVEINIAANRGMDFYDVSLVDGYNLPVSVATRGGTGDCKATGFVLASKASLTLGVQAPWKGRFWARTRCTTNSGKFTCETADCSTGQVACTSCRANVNAVCPAELQVKGSDASVLACKSACTAFNQPQYCCTGAFDTART
    

Molecular Weight25835.09 Da

Isoelectric Point (pI)8.57

Net Charge (pH 7.0)5.69

Net Charge (pH 7.4) 5.16

Charge Density (pH 7.0) 0.0234

GRAVY Index-0.05

Hydrophobic Moment 0.62

Boman Index0.08

Instability Index34.47

Aliphatic Index 64.36

Aromaticity 0.0988

Extinction Coeff. Reduced 29910.00

Extinction Coeff. Oxidized 30910.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0042017 VERIFIED: NO

Provenance & Taxonomy

OrganismCastanea sativa [Plant]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Signaling Enzyme inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme