Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length141 amino acids

Chemical FormulaC700H1128N194O187S4

DescriptionStandard

        PVPLPLAEEPMLLLGVTEFVANSAAFVYFTAGALRWTVTGDMLPRRFPLRLSTKGLGLFAPQLQELYPDRPMELRVWARRQPLLSCRPDGLRLALHGTAETSVLLPNGTRAPAFLLHLDANVTGKPVLTASRIGVTVSLRG
    

Molecular Weight15381.89 Da

Isoelectric Point (pI)10.35

Net Charge (pH 7.0)5.14

Net Charge (pH 7.4) 4.95

Charge Density (pH 7.0) 0.0365

GRAVY Index0.19

Hydrophobic Moment 0.58

Boman Index0.12

Instability Index47.27

Aliphatic Index 107.23

Aromaticity 0.0709

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5970.65

LogP -49.78

H-bond Donors 210.0

H-bond Acceptors 198.0

Rotatable Bonds 485.0

Heavy Atoms 1085.0

Ring Count 28.0

Amide Bonds 146.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0400380 VERIFIED: NO

Provenance & Taxonomy

OrganismCrypturellus soui [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria