Peptide Database

Peptide NameCycloviolacin O18

Function Ontology

—

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC126H204N34O40S6

DescriptionStandard

        GIPCGESCVFIRCTITALLGCSCSNNVCY
    

Molecular Weight3027.56 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0103

GRAVY Index0.90

Hydrophobic Moment 0.35

Boman Index0.29

Instability Index38.30

Aliphatic Index 90.69

Aromaticity 0.0690

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1176.09

LogP -14.68

H-bond Donors 47.0

H-bond Acceptors 46.0

Rotatable Bonds 94.0

Heavy Atoms 206.0

Ring Count 3.0

Amide Bonds 30.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0205579 VERIFIED: YES

Provenance & Taxonomy

OrganismCarapichea ipecacuanha [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)