Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC358H576N88O97S6

DescriptionStandard

        MDLFNSIVEIAGTFKISMDTSTKVYDAVMAGADMWAVISIIAAVTGPLAIGGAVVFYMIKRKIKGMARSAAIAW
    

Molecular Weight7857.32 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)1.50

Net Charge (pH 7.4) 1.27

Charge Density (pH 7.0) 0.0203

GRAVY Index0.82

Hydrophobic Moment 0.77

Boman Index0.34

Instability Index21.00

Aliphatic Index 108.24

Aromaticity 0.0946

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2916.43

LogP -20.63

H-bond Donors 104.0

H-bond Acceptors 105.0

Rotatable Bonds 259.0

Heavy Atoms 549.0

Ring Count 10.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0085778 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus larvae subsp. larvae [Bacterium]

FamilyCircular bacteriocin

Structure & Mods

Configcyclic peptide topology reported [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

RECORD: Rec_0090199 VERIFIED: NO

Provenance & Taxonomy

OrganismPaenibacillus larvae subsp. larvae DSM 25719 [Bacterium]

FamilyBacteriocin

Tax ID697286

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitynoncanonical stereochemical modification [Modified]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal