Peptide Database

Peptide NameHepalatide

Function Ontology

Antiviral

Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HBV

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor

Standard StatusStandard

Sequence Length47 amino acids

Chemical FormulaC233H324N64O73

DescriptionStandard

        GTNLSVPNPLGFFPDHQLDPAFGANSNNPDWDFNPNKDHWPEANQVG
    

Molecular Weight5189.45 Da

Isoelectric Point (pI)4.16

Net Charge (pH 7.0)-5.06

Net Charge (pH 7.4) -5.37

Charge Density (pH 7.0) -0.1076

GRAVY Index-1.00

Hydrophobic Moment 0.37

Boman Index0.01

Instability Index11.73

Aliphatic Index 43.62

Aromaticity 0.1277

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2170.74

LogP -25.10

H-bond Donors 65.0

H-bond Acceptors 70.0

Rotatable Bonds 152.0

Heavy Atoms 370.0

Ring Count 17.0

Amide Bonds 56.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0309002 VERIFIED: YES

Provenance & Taxonomy

OrganismHepatitis B virus [Virus]

FamilypreS1-derived entry inhibitor

Tax ID10407

Structure & Mods

Configbranched peptide architecture [Branched]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsNTCP-binding preS1-derived therapeutic peptide

Bio-Activity Profile

Function

Antiviral Anti-HBV Entry inhibitor

TargetHepatitis B virus