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MYP_037648
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Basic Information
Tachystatin-A2 (crabs, Arthropods, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
44 amino acids
C219H336N66O61S6
Standard
Sequence
YSRCQLQGFNCVVRSYGLPTIPCCRGLTCRSYFPGSTYGRCQRY
Physicochemical Analysis
5061.81 Da
9.34
5.70
5.40
0.1294
-0.33
0.59
-0.10
34.62
48.64
0.1591
7450.00
7825.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2074.77
-24.41
82.0
73.0
156.0
352.0
10.0
47.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001919 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
3 μg/mL
IC50
PaperPubMed PMID: 10473569 | PubMed PMID: 11959852 PMID10473569;11959852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10473569/
RECORD: Rec_0015821 VERIFIED: YES
Provenance & Taxonomy
Atlantic horseshoe [Animal]; Arthropoda [Animal]
33208; 6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID8939880 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8939880/
RECORD: Rec_0016725 VERIFIED: NO
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0024663 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
4-24; 11-29; 23-41
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Host defense
PaperPDB 1CIX structural record; NMR; chain A; residues 1-44
RECORD: Rec_0030901 VERIFIED: YES
Provenance & Taxonomy
Tachypleus tridentatus [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Pichia pastoris
0.5 μg/mL
IC50
PaperPubMed PMID: 10473569 | PubMed PMID: 11959852 PMID10473569;11959852 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10473569/
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