Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length189 amino acids

Chemical FormulaC913H1482N268O254S8

DescriptionStandard

        PAALPAAQEPMLLLAVTESVANSAASTYFTAGALRRNISSDMLPRRFPLQLRTKSMGLFSPELQQRYPDQPMELHLSARRQPLLSCRPDALHGALFGSAEAFVVLPNATRVPAFLLNVDANVTGKPTITRNRLGGTVSLTGGAEPCLRRARLRGLPVSQVKRLETLLKFGLWLFGVPRANSECCPHPVP
    

Molecular Weight20533.70 Da

Isoelectric Point (pI)10.50

Net Charge (pH 7.0)10.20

Net Charge (pH 7.4) 9.91

Charge Density (pH 7.0) 0.0540

GRAVY Index-0.03

Hydrophobic Moment 0.57

Boman Index0.03

Instability Index64.06

Aliphatic Index 93.49

Aromaticity 0.0582

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8730.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8258.86

LogP -103.48

H-bond Donors 290.0

H-bond Acceptors 275.0

Rotatable Bonds 656.0

Heavy Atoms 1443.0

Ring Count 34.0

Amide Bonds 202.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0184061 VERIFIED: NO

Provenance & Taxonomy

OrganismOceanites oceanicus (Wilson`s storm petrel) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria