Peptide Database

Peptide NameSLAY-screened peptide P3826

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC77H114N14O23S2

DescriptionStandard

        ESCSLYDYLAFLLM
    

Molecular Weight1667.94 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-2.17

Net Charge (pH 7.4) -2.36

Charge Density (pH 7.0) -0.1553

GRAVY Index0.93

Hydrophobic Moment 0.27

Boman Index0.39

Instability Index63.24

Aliphatic Index 118.57

Aromaticity 0.2143

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 597.14

LogP -1.95

H-bond Donors 22.0

H-bond Acceptors 23.0

Rotatable Bonds 52.0

Heavy Atoms 116.0

Ring Count 3.0

Amide Bonds 13.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0216881 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/