Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC340H546N90O91S8

DescriptionStandard

        MTQLLLLLVALLVLGHVPTGRSEFKRCWNGQGACRAYCTKYEAYMHLCSDATLCCLPYGLKPVKTEKV
    

Molecular Weight7607.04 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)3.62

Net Charge (pH 7.4) 3.19

Charge Density (pH 7.0) 0.0532

GRAVY Index0.23

Hydrophobic Moment 0.49

Boman Index0.12

Instability Index54.70

Aliphatic Index 97.50

Aromaticity 0.0882

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2876.60

LogP -21.94

H-bond Donors 107.0

H-bond Acceptors 105.0

Rotatable Bonds 247.0

Heavy Atoms 529.0

Ring Count 12.0

Amide Bonds 70.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0095992 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus x Bos taurus [Animal]

FamilyDefensin

Tax ID30522

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0208340 VERIFIED: NO

Provenance & Taxonomy

OrganismBos indicus [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized linear peptide scaffold [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

RECORD: Rec_0237707 VERIFIED: NO

Provenance & Taxonomy

OrganismBos mutus [Animal]

FamilyDefensin

Tax ID30521

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0330255 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence