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MYP_037575
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Sensory / Food function ▸ Taste-active peptide
Sensory / Food function ▸ Taste-active peptide ▸ Bitter peptide
Sensory / Food function ▸ Taste-active peptide ▸ Umami peptide
Standard
2 amino acids
C9H16N2O5
Standard
Sequence
VD
Physicochemical Analysis
232.23 Da
4.30
-1.26
-1.48
-0.6309
0.35
0.76
0.09
-70.15
145.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
129.72
-0.99
4.0
4.0
6.0
16.0
0.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0058173 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Sensory peptide
Structure & Mods
linear contiguous peptide sequence [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Bitter
0.08 Rcaf
Relative bitterness (Rcaf)
PaperRole of the hydrophobic amino acid residue in the bitterness of peptides. Agric. Biol. Chem., 52, 91-94, 1988
RECORD: Rec_0091585 VERIFIED: YES
Provenance & Taxonomy
Unknown [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Taste Enzyme inhibitory ACE inhibitory
Angiotensin-I converting enzyme
709100 μg/mL
IC50
RECORD: Rec_0119339 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antidiabetic DPP-IV inhibitory
human dipeptidyl peptidase IV
PaperLan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.. Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73, 2015. PMID25577052 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25577052/
RECORD: Rec_0127461 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Sensory peptide
Structure & Mods
linear contiguous peptide sequence [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Sour
PaperRole of the hydrophobic amino acid residue in the bitterness of peptides. Agric. Biol. Chem., 52, 91-94, 1988
RECORD: Rec_0149293 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperQuantitative structure-activity relationship study of bitter di- and tri-peptides including relationship with angiotensin I-converting enzyme inhibitory activity. PMID17117396 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17117396/
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