‹ ›
MYP_037543
← PREVIOUS NEXT → BACK
Basic Information
Datucin
Antimicrobial
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Standard
31 amino acids
C170H251N47O39S2
Standard
Sequence
TFPKCAPTRPPGPKPCDINNFKSKFWHIWRA
Physicochemical Analysis
3641.23 Da
10.06
4.46
4.19
0.1440
-0.85
0.55
-0.10
51.97
31.61
0.1613
11000.00
11125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1355.89
-10.23
47.0
47.0
106.0
258.0
14.0
32.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0024731 VERIFIED: YES
Provenance & Taxonomy
Datura stramonium [Plant]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans
1 μM
MIC
PMID23193597 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23193597/
RECORD: Rec_0091959 VERIFIED: YES
Provenance & Taxonomy
Datura stramonium [Animal]
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
PaperPubMed PMID: 23193597 PMID23193597 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23193597/
RECORD: Rec_0137844 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0351975 VERIFIED: YES
Provenance & Taxonomy
Datura stramonium [Plant]
glycopeptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Proline hydroxylation reported
Bio-Activity Profile
Antimicrobial Antifungal Antibiofilm
Candida albicans
1 μM
MIC
PMID23193597 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23193597/
RECORD: Rec_0368292 VERIFIED: YES
Provenance & Taxonomy
Datura stramonium [Plant]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Acetylation
P10, P11, and P15 are hydroxylated prolines (XXK). In addition, the C-terminus of the peptide is attached with N-acetylglucosaminylasparagine (-GlcNAc-)Asn
Bio-Activity Profile
Antimicrobial Antifungal
a clinical multidrug-resistant strain Candida albicans in both the planktonic
PaperA Novel Hydroxyproline Rich Glycopeptide from Pericarp of Datura stramonium: Proficiently Eradicate the Biofilm of Antifungals Resistant Candida albicans
1 2 NEXT LAST
Showing 5 records on this page · Page 1 of 2