Peptide Database

Peptide NameHNHc domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length606 amino acids

Chemical FormulaC2893H4724N834O916S5

DescriptionStandard

        MVNGDSNDSMTVSGSSDNGGRGTGPEGNGDSGGSYGGRARAVNFSKTPEKQTFVNPYLLTIPANLAIIEGTWGVTINTTTLTSPLGRLASLLESSLPMAGRLVGIAGALLPTRIEPDTIDPAFREHQRQLANLVTNQKLHSQTYALTALPVSIVTDIPAKDISRQKTVSVKIAVEQVVSPEKNKVTQAIIKSPQTINVVKAKKTERTGVYSVDIAPGKPALQIGLSDKKPSKSFKTPSYDNVKPESVISSTTSETYQGIVDFGDDHAPIYISISKSLTVEEEKKAIEDAKQKEQEYLDTHPIAAAERELSDAKKALDDANKNVQSEQLALDNLRNSAEGLALKNPVAHPITSSSAGFVHIPIYSGGGANFTATATIDTVDNLNQLLRNGGNTYVNSVLQWVEITDPIEGIEPDGIKVGNSIREATVEEYDKLRQRLLSTKNKIKEAEKKLEIALETKKKAEAKEKKAKDKKEKEEKRNKPGTATGNGKKVGDKWLNDAGKENGVPIPEQVANKLRGKKFKTCDDFRKKFWEAVSKDPVLRKQFIKGNQNRMSKGLAPRARNKGTVGGRRSFEIHHDTPISEGGEVYNIDNLRIVTPKRHIDIHRGK
    

Molecular Weight66005.82 Da

Isoelectric Point (pI)9.33

Net Charge (pH 7.0)15.44

Net Charge (pH 7.4) 14.50

Charge Density (pH 7.0) 0.0255

GRAVY Index-0.63

Hydrophobic Moment 0.70

Boman Index-0.10

Instability Index35.41

Aliphatic Index 80.96

Aromaticity 0.0462

Extinction Coeff. Reduced 39880.00

Extinction Coeff. Oxidized 39880.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0032086 VERIFIED: NO

Provenance & Taxonomy

OrganismProvidencia heimbachae ATCC 35613 [Bacterium]

FamilyColicin pyosin nuclease

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Anti-Gram-negative Hydrolase Non-hemolytic

TargetEscherichia coli