Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC452H717N121O137S9

DescriptionStandard

        MDTVLTLTALQVMKTFLFLFAVFFFLDPAKNAFFDEKCSRINGRCTESCLKNEELIALCQKNLKCCVTVQPCGRDKGDELDEDSGYNRTRG
    

Molecular Weight10326.84 Da

Isoelectric Point (pI)5.35

Net Charge (pH 7.0)-1.55

Net Charge (pH 7.4) -1.90

Charge Density (pH 7.0) -0.0171

GRAVY Index-0.14

Hydrophobic Moment 0.52

Boman Index-0.03

Instability Index30.72

Aliphatic Index 77.14

Aromaticity 0.0989

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4208.53

LogP -41.37

H-bond Donors 151.0

H-bond Acceptors 145.0

Rotatable Bonds 350.0

Heavy Atoms 719.0

Ring Count 11.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0264309 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyBeta-defensin; Defensin

Tax ID10116

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic