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MYP_037485
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Basic Information
Cocaine & amphetamine-regulated transcript peptide, CART [1-39]
Cardiovascular
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
39 amino acids
C194H319N51O67
Standard
Sequence
QEDAELQPRALDIYSAVEDASHEKELIEALQEVLKKLKS
Physicochemical Analysis
4437.91 Da
4.53
-5.13
-5.41
-0.1317
-0.64
0.68
-0.13
53.96
107.69
0.0256
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1938.18
-16.95
64.0
63.0
157.0
312.0
3.0
41.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0164619 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Feeding Behavior
RECORD: Rec_0320981 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
CART(1-39)
9913
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
14:Phosphotyrosine; 21:Phosphoserine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation ACE inhibitory Feeding regulator
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for CART(1-39) (Bos taurus): PMID 15670137 PMID15670137 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15670137/
RECORD: Rec_0370370 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0413520 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]
CART
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Neuromodulator
Evidence URLhttps://www.uniprot.org/uniprotkb/CART_BOVIN/entry