Peptide Database

Peptide NameApl_AvBD-2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC200H313N63O49S7

DescriptionStandard

        PGLSSPRRDMFFCRKGSCHFGRCPIHLVKVGSCFGFRSCCK
    

Molecular Weight4608.47 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)7.07

Net Charge (pH 7.4) 6.82

Charge Density (pH 7.0) 0.1725

GRAVY Index-0.09

Hydrophobic Moment 0.60

Boman Index-0.07

Instability Index78.09

Aliphatic Index 42.68

Aromaticity 0.1220

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1779.12

LogP -19.55

H-bond Donors 72.0

H-bond Acceptors 65.0

Rotatable Bonds 149.0

Heavy Atoms 319.0

Ring Count 10.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0359060 VERIFIED: YES

Provenance & Taxonomy

OrganismPterocles gutturalis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)