Peptide Database

Peptide NameMegin 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC110H158N24O22S2

DescriptionStandard

        FLKGCWTKWYSLKPKCPF
    

Molecular Weight2232.71 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)3.74

Net Charge (pH 7.4) 3.50

Charge Density (pH 7.0) 0.2075

GRAVY Index-0.31

Hydrophobic Moment 0.34

Boman Index0.08

Instability Index17.31

Aliphatic Index 43.33

Aromaticity 0.2778

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 736.79

LogP -0.99

H-bond Donors 28.0

H-bond Acceptors 28.0

Rotatable Bonds 67.0

Heavy Atoms 158.0

Ring Count 9.0

Amide Bonds 17.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0227989 VERIFIED: YES

Provenance & Taxonomy

OrganismMegophrys minor [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus aureus ATCC2592

Activity6.25 μg/mL

MethodMIC

RECORD: Rec_0232858 VERIFIED: YES

Provenance & Taxonomy

OrganismMegophrys minor [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antifungal

TargetCandida albicans

Activity50 μg/mL

MethodMIC

RECORD: Rec_0258550 VERIFIED: YES

Provenance & Taxonomy

OrganismAmphibian skin [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Disulfide5-16

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic

TargetRabbit red blood cells :3

RECORD: Rec_0277904 VERIFIED: YES

Provenance & Taxonomy

OrganismMegophrys minor [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus

Activity6.25 μg/mL

MethodMIC

RECORD: Rec_0293016 VERIFIED: YES

Provenance & Taxonomy

OrganismAmphibian skin [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Disulfide5-16

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal

Targetdysenteriae

Activity3 μg/mL

MethodMIC

FIRST PREV 1 2 3 4 5 NEXT LAST

Showing 5 records on this page Ã‚Â· Page 3 of 5