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MYP_037438
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Basic Information
Megin 1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
18 amino acids
C110H158N24O22S2
Standard
Sequence
FLKGCWTKWYSLKPKCPF
Physicochemical Analysis
2232.71 Da
9.60
3.74
3.50
0.2075
-0.31
0.34
0.08
17.31
43.33
0.2778
12490.00
12615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
736.79
-0.99
28.0
28.0
67.0
158.0
9.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0001221 VERIFIED: YES
Provenance & Taxonomy
Amphibian skin [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
5-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PMID27114317 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27114317/
RECORD: Rec_0060686 VERIFIED: YES
Provenance & Taxonomy
Amphibian skin [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
5-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
PMID27114317 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27114317/
RECORD: Rec_0076567 VERIFIED: YES
Provenance & Taxonomy
Megophrys minor [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
5-16
Bio-Activity Profile
Antimicrobial Antifungal
B. dysenteriae
3 μg/mL
MIC
PaperTwo novel antimicrobial peptides from skin venoms of spadefoot toad Megophrys minor.
RECORD: Rec_0118186 VERIFIED: YES
Provenance & Taxonomy
Amphibian skin [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
5-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Hemolytic
Human red blood cells: 2
PMID27114317 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27114317/
RECORD: Rec_0147278 VERIFIED: YES
Provenance & Taxonomy
Amphibian skin [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Amidation
5-16
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus (ATCC 2592)
6.25 μg/mL
MIC
PMID27114317 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27114317/
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