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MYP_037415
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Regulatory peptide ▸ Stimulation activity
Standard
6 amino acids
C37H52N6O11
Standard
Sequence
YLGYLE
Physicochemical Analysis
756.84 Da
4.60
-1.23
-1.44
-0.2056
0.18
0.24
0.40
-5.82
130.00
0.3333
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
286.58
0.31
10.0
10.0
22.0
54.0
2.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0007055 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antioxidant
PaperAmigo L., Mart¨ªnez-Maqueda D., Hern¨¢ndez-Ledesma B.. In silico and in vitro analysis of multifunctionality of animal food-derived peptides. Foods, 9, 991, 2020.
RECORD: Rec_0089915 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
alpha-S1-Casein-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive Macrophage-modulating
Angiotensin-converting enzyme (ACE)
85.76 μM
IC50
PaperIn Silico and In Vitro Analysis of Multifunctionality of Animal Food-Derived Peptides | Amigo, L. et al. | DOI: 10.3390/foods9080991 Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0131438 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casomorphin
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Mucin secretagogue Gastroprotective
HT29-MTX cells
Mucin secretion assay
PaperFood-Derived Peptides Stimulate Mucin Secretion and Gene Expression in Intestinal Cells | Martinez-Maqueda, D. et al. | DOI: 10.1021/jf301279k Evidence URLhttps://www.uniprot.org/uniprotkb/P02662/entry
RECORD: Rec_0138824 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Casein-derived peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
[3H]-dihydromorphine binding
45.0 μM
IC50
RECORD: Rec_0215988 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid
opioid receptor
45.0
PaperLoukas S., Varoucha D., Zioudrou C., Streaty R. A., Klee W. A.. Opioid activities and structures of alpha-casein-derived exorphins. Biochemistry, 22, 4567-4573, 1983.
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