‹ ›
MYP_037353
← PREVIOUS NEXT → BACK
Basic Information
Unnamed
Antiviral
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor Of Endothelin-1 Release
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Therapeutic / Biomedical activity ▸ Regenerative medicine ▸ Bone metabolism ▸ Osteoanabolic activity
Standard
7 amino acids
C37H64N12O8S
Standard
Sequence
ALPMHIR
Physicochemical Analysis
837.04 Da
9.80
0.88
0.64
0.1261
0.39
0.47
0.13
169.91
125.71
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
319.71
-1.09
11.0
11.0
25.0
58.0
2.0
6.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0147819 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Lactoglobulin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
14 μM
IC50
PaperAntihypertensive effect of the bovine casein-derived peptide Met-Lys-Pro | Yamada, A. et al. | DOI: 10.1016/j.foodchem.2014.09.098 Evidence URLhttps://www.uniprot.org/uniprotkb/P02754/entry
RECORD: Rec_0172064 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Inhibitor Of Endothelin-1 Release
PaperMaes W., Van Camp J., Vermeirssen V., Hemeryck M., Ketelslegers J. M., Schrezenmeir J., Van Oostveldt P., Huyghebaert A.. Influence of the lactokinin Ala-Leu-Pro-Met-His-Ile-Arg (ALPMHIR) on the release of endothelin-1 by endothelial cells. Regulatory Peptides, 118, 105-109, 2004.
RECORD: Rec_0181727 VERIFIED: NO
Provenance & Taxonomy
Sheep milk [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
ACE
42.6 μM
IC50
RECORD: Rec_0197293 VERIFIED: NO
Provenance & Taxonomy
Ovis aries [Animal]
ACE-inhibitory peptide
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
62.6 μM
IC50
PaperBioactive Peptides of Buffalo, Camel, Goat, Sheep, Mare, and Yak Milks and Milk Products
RECORD: Rec_0221378 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
43.0
IC50
PaperMullally M., Meisel H., FitzGerald R. J.. Identification of a novel angiotensin I-converting enzyme inhibitory peptide corresponding to a tryptic fragment of bovine beta-Lg. FEBS Lett., 402, 99-102, 1997.
FIRST PREV 1 2 3 4 NEXT LAST
Showing 5 records on this page · Page 2 of 4