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MYP_037353
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Basic Information
Unnamed
Antiviral
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ Inhibitor Of Endothelin-1 Release
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Therapeutic / Biomedical activity ▸ Regenerative medicine ▸ Bone metabolism ▸ Osteoanabolic activity
Standard
7 amino acids
C37H64N12O8S
Standard
Sequence
ALPMHIR
Physicochemical Analysis
837.04 Da
9.80
0.88
0.64
0.1261
0.39
0.47
0.13
169.91
125.71
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
319.71
-1.09
11.0
11.0
25.0
58.0
2.0
6.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012229 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
ACE-inhibitory peptide
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperBioactive peptides derived from milk proteins and their health beneficial potentials: an update. PMID21773582 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21773582/
RECORD: Rec_0017015 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperThe potential role of milk-derived peptides in cardiovascular disease. PMID21779574 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21779574/
RECORD: Rec_0033369 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory Osteoanabolic ACE inhibitory
Angiotensin-converting enzyme
43 μM
IC50
RECORD: Rec_0085282 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0146210 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
beta-Lactoglobulin-derived
9913
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
ACE inhibitory Antihypertensive
Angiotensin-converting enzyme (ACE)
42.6 μM
IC50
PaperIdentification of a novel angiotensin-I-converting enzyme inhibitory peptide corresponding to a tryptic fragment of bovine β-lactoglobulin | Mullally, M. et al. | DOI: 10.1016/s0014-5793(96)01503-7 Evidence URLhttps://www.uniprot.org/uniprotkb/P02754/entry
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