Peptide Database

Peptide NameDefensin-7

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC463H714N118O134S9

DescriptionStandard

        MRTLTLLSAVLLVALQTWAEPLQATADEMPAQEQPPAGNQDVLIYFSGDESSFLQVPGSMKGLICHCRVLYCLFGEHLGGTCFIHGERYPICCY
    

Molecular Weight10365.92 Da

Isoelectric Point (pI)4.84

Net Charge (pH 7.0)-5.28

Net Charge (pH 7.4) -5.76

Charge Density (pH 7.0) -0.0562

GRAVY Index0.25

Hydrophobic Moment 0.44

Boman Index0.21

Instability Index43.44

Aliphatic Index 93.40

Aromaticity 0.0957

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11835.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3950.98

LogP -33.13

H-bond Donors 139.0

H-bond Acceptors 141.0

Rotatable Bonds 329.0

Heavy Atoms 724.0

Ring Count 19.0

Amide Bonds 100.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0241458 VERIFIED: NO

Provenance & Taxonomy

OrganismTheropithecus gelada [Animal]

FamilyDefensin

Tax ID9565

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Non-hemolytic Non-ribosomal