Peptide Database

Peptide NameBrevinin-1Pb

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC365H572N84O104S4

DescriptionStandard

        MFTLNKFLLLLFFLGTINLSFCEEENAEEERIDEPDETDVEVEKRFLPIIAGIAAKVFPKIFCAISKKC
    

Molecular Weight7929.21 Da

Isoelectric Point (pI)4.58

Net Charge (pH 7.0)-5.50

Net Charge (pH 7.4) -5.79

Charge Density (pH 7.0) -0.0798

GRAVY Index0.26

Hydrophobic Moment 0.61

Boman Index0.14

Instability Index39.27

Aliphatic Index 104.64

Aromaticity 0.1159

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3010.99

LogP -17.48

H-bond Donors 103.0

H-bond Acceptors 103.0

Rotatable Bonds 268.0

Heavy Atoms 557.0

Ring Count 11.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141708 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates pipiens [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus