Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length415 amino acids

Chemical FormulaC2042H3223N543O575S16

DescriptionStandard

        MNVRGFQLPSRQVILVPDVGLKLFIGNASVKISGKWKAQKSFIKTSGNFDLTVEGVSISAGVRVGSDPASGKATVTCSGCSSHISSVGVHIAGSRLGWLIRLFRKQIESSIRNNIQDKICKVVANSVSSKLQPFFQNLPVMAKIDAVAGIDYRLVAPPTATSEYLDGHLKGEFFSWADPMPPPFAPPALEFPAIHDRMVYLGLSEYFFNTAGLVYYEAGALQLTLTDDMIPEKSSFRLTTRFFGTFLPQVAQMFPDMNMQLDVSVSTPPHLSMQSSGLVLTPYLEAETFAILPNSSLASLFLLGLSTNASVRVGAMASRLVGELELDRLLLELKHSNIGPFPVALLQAIMDYAVPTLVLPRVNQKLQRGFPLPVPSHFQLYNPVLRSHQGVLLFGADVRHAEVAPSAGGCRRSCS
    

Molecular Weight45092.77 Da

Isoelectric Point (pI)9.03

Net Charge (pH 7.0)6.27

Net Charge (pH 7.4) 5.45

Charge Density (pH 7.0) 0.0151

GRAVY Index0.17

Hydrophobic Moment 0.76

Boman Index0.15

Instability Index43.56

Aliphatic Index 97.95

Aromaticity 0.0867

Extinction Coeff. Reduced 29910.00

Extinction Coeff. Oxidized 30160.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0102943 VERIFIED: NO

Provenance & Taxonomy

OrganismMicrocebus murinus (Gray mouse lemur) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria