Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC348H533N107O103S10

DescriptionStandard

        MCILESTAVPFPEDFRDEVGSIDSPVGEHQQPGGESLRPPEHFRFKHRRHLSLCRWCCNCCNNKGCGSCCKF
    

Molecular Weight8184.26 Da

Isoelectric Point (pI)6.86

Net Charge (pH 7.0)-0.22

Net Charge (pH 7.4) -0.79

Charge Density (pH 7.0) -0.0031

GRAVY Index-0.58

Hydrophobic Moment 0.52

Boman Index-0.13

Instability Index73.66

Aliphatic Index 45.97

Aromaticity 0.0833

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3349.41

LogP -38.10

H-bond Donors 123.0

H-bond Acceptors 117.0

Rotatable Bonds 263.0

Heavy Atoms 568.0

Ring Count 17.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0399386 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmo trutta [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal