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MYP_037215
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Basic Information
Cathelicidin-like peptide
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
34 amino acids
C208H338N58O38
Standard
Sequence
KRFKKFFKKLKNSVKKRVKKFFRKPRVIGVTFPF
Physicochemical Analysis
4259.27 Da
12.00
14.75
14.53
0.4338
-0.73
0.82
-0.35
21.38
57.06
0.2059
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1623.41
-7.82
59.0
53.0
151.0
304.0
9.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0050693 VERIFIED: YES
Provenance & Taxonomy
Bothrops atrox [Animal]
Cathelicidin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
32 μg/mL
MIC
PMID25100358 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25100358/
RECORD: Rec_0052726 VERIFIED: YES
Provenance & Taxonomy
American pit vipers [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic
S. pyogenes clinical isolate
3.8 μM
MIC
PaperVipericidins: a novel family of cathelicidin-related peptides from the venom gland of South American pit vipers.
RECORD: Rec_0058238 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 47.1%, E 0.0%, T 5.9%, C 47.1% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
RECORD: Rec_0064036 VERIFIED: YES
Provenance & Taxonomy
Bothrops atrox [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
0.06 μM
MIC
RECORD: Rec_0090615 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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