Peptide Database

Peptide NameSarafotoxin-m4

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC116H179N31O40S5

DescriptionStandard

        CSCNNMSDKECLNFCNLDIIWENV
    

Molecular Weight2808.17 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-3.27

Net Charge (pH 7.4) -3.54

Charge Density (pH 7.0) -0.1364

GRAVY Index-0.10

Hydrophobic Moment 0.33

Boman Index0.03

Instability Index58.01

Aliphatic Index 77.08

Aromaticity 0.0833

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5750.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1179.54

LogP -13.00

H-bond Donors 42.0

H-bond Acceptors 42.0

Rotatable Bonds 93.0

Heavy Atoms 192.0

Ring Count 3.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0377638 VERIFIED: YES

Provenance & Taxonomy

OrganismAtractaspis microlepidota microlepidota [Animal]

FamilySarafotoxin-m4

Tax ID172021

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide1-15; 3-11

Bio-Activity Profile

Function

Vasoactive Vasoconstrictor

Half-LifeMammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour