Peptide Database

Peptide NameS-type pyocin domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length619 amino acids

Chemical FormulaC2865H4652N814O879S20

DescriptionStandard

        MMAENQPAPLTPAPPGMVSLGVNADGEEVMTVIGGDGGAGFSGGHANIVPGSGSILADQRKKTLSRLQAECSAAIEATAKWSTENLEKTMAAQAERIRAATAAQQSAKASLDRLMQQLKDVTDKALQKARSGPSVTDLAHQNNQELAALGEQIGRQKALNEARKKAEREAKKAEETYQAALLAQEEAQRQQAEVERELKEARAHEAAAKAKAEADRVAAEKEEAERLKAEEAQKALFAKVGIQGTPVYTQEMVKAVSVLMLKPGVILLNRAPGMIQMAAVAVRAPAALPGVASAVITATAEFSGWISSALWRGVVGVAGAATATTAGAMVAAASTIFFSPRAGGGNDSKVPGRDIEIMAAQARLFTAGKLIIDPGMKSVDLPVRGFITMEMDGRQSLKLVKTGTGGISATVPVLSGVRDKASGLDKIMVPAVDGAPSLSILINPVPFGPAAPSHTGNSTPVPVTPVHTGTEVKQADSIVTTSLPVADVPPLQDFIYWQPDATGTGVEPIYVMLSSLPKSVNHKHKHYPPKGVSWKDIVNATANGGSAKFKPDVNIAEIDIDAWKNGQMTAKHPTWKVKKYDHVIGAYAGKETQWVVVKESQGVVHSHPISEQKAKEYMK
    

Molecular Weight65205.81 Da

Isoelectric Point (pI)8.85

Net Charge (pH 7.0)5.62

Net Charge (pH 7.4) 4.62

Charge Density (pH 7.0) 0.0091

GRAVY Index-0.21

Hydrophobic Moment 0.74

Boman Index0.04

Instability Index35.73

Aliphatic Index 83.18

Aromaticity 0.0420

Extinction Coeff. Reduced 55920.00

Extinction Coeff. Oxidized 55920.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0238814 VERIFIED: YES

Provenance & Taxonomy

OrganismKlebsiella grimontii [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)