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MYP_037131
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Basic Information
NLP-31
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Standard
53 amino acids
C255H328N72O69S
Standard
Sequence
QWGYGGYGRGYGGYGGYGRGYGGYGGYGRGYGGYGRGMYGGYGRPYGGYGWGK
Physicochemical Analysis
5537.84 Da
9.70
5.75
5.52
0.1084
-1.15
0.53
0.08
-14.70
0.00
0.3019
31860.00
31860.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2261.14
-24.02
86.0
76.0
166.0
397.0
19.0
53.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0008075 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
NLP
6239
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
PaperNat Immunol. 2004 May;5(5):488-94 | http://www.ncbi.nlm.nih.gov/pubmed/15048112 PMID15048112 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15048112/
RECORD: Rec_0032004 VERIFIED: NO
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
PMID15048112 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15048112/
RECORD: Rec_0051346 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
6239
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
the Gram+ Micrococcus luteus
5.7-11.4 μM
MIC
PaperTLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM.
RECORD: Rec_0182060 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]; Animalia [Animal]
6239; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID150481123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/150481123/
RECORD: Rec_0197114 VERIFIED: YES
Provenance & Taxonomy
Caenorhabditis elegans [Animal]
Neuropeptide-like protein
6239
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
7:Tyrosine amide; 17:Tyrosine amide; 27:Tyrosine amide; 34:Tyrosine amide; 42:Tyrosine amide; 51:Tryptophan amide
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Antibacterial Antifungal Neuropeptide Neuromodulator
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Neuropeptide-like protein 31 (Caenorhabditis elegans): PMID 15048112 PMID15048112 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15048112/
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