Peptide Database

Peptide NameC-type natriuretic peptide

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC100H161N31O28S2

DescriptionStandard

        GWNRGCFGLKLDRIGSLSGLGC
    

Molecular Weight2309.67 Da

Isoelectric Point (pI)8.96

Net Charge (pH 7.0)1.74

Net Charge (pH 7.4) 1.51

Charge Density (pH 7.0) 0.0791

GRAVY Index0.12

Hydrophobic Moment 0.45

Boman Index0.11

Instability Index5.76

Aliphatic Index 88.64

Aromaticity 0.0909

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 960.88

LogP -10.59

H-bond Donors 37.0

H-bond Acceptors 32.0

Rotatable Bonds 77.0

Heavy Atoms 161.0

Ring Count 3.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0118268 VERIFIED: YES

Provenance & Taxonomy

OrganismAnguilla japonica [Animal]

FamilyC-type natriuretic peptide

Tax ID7937

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-22

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0241126 VERIFIED: NO