Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC436H721N137O140S7

DescriptionStandard

        MRTLAILAAILLFALLAQAKSLQETADEAATQEQPGEDDQDLAVSFEENGLSTLRDSGSQARRTCRCRIRRCRGLESSFGNCILHGQFAKLCCR
    

Molecular Weight10346.68 Da

Isoelectric Point (pI)6.55

Net Charge (pH 7.0)-0.45

Net Charge (pH 7.4) -0.82

Charge Density (pH 7.0) -0.0048

GRAVY Index-0.23

Hydrophobic Moment 0.63

Boman Index-0.10

Instability Index47.87

Aliphatic Index 86.38

Aromaticity 0.0426

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4538.72

LogP -54.50

H-bond Donors 166.0

H-bond Acceptors 148.0

Rotatable Bonds 356.0

Heavy Atoms 720.0

Ring Count 6.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0147844 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca nemestrina [Animal]

FamilyDefensin

Tax ID9545

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence