Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length167 amino acids

Chemical FormulaC815H1289N245O245S9

DescriptionStandard

        MMYRSASSNRRKEQSSMAKVQFTKRQETSQIFVHCSATKATMDVGVREIRQWHKEQGWLDVGYHFIIRRDGTVEAGRDQDAVGSHVKGYNSTSVGVCLVGGIDAKGNPEANFTPAQMQSLRSLLVELKVQYAGAVLMAHHDVAPKACPSFDLKRWWEKNELVTSDRG
    

Molecular Weight18728.03 Da

Isoelectric Point (pI)9.22

Net Charge (pH 7.0)5.01

Net Charge (pH 7.4) 4.41

Charge Density (pH 7.0) 0.0300

GRAVY Index-0.52

Hydrophobic Moment 0.75

Boman Index-0.09

Instability Index52.60

Aliphatic Index 68.86

Aromaticity 0.0778

Extinction Coeff. Reduced 27960.00

Extinction Coeff. Oxidized 28085.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7966.75

LogP -87.86

H-bond Donors 283.0

H-bond Acceptors 265.0

Rotatable Bonds 631.0

Heavy Atoms 1314.0

Ring Count 27.0

Amide Bonds 181.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0104794 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella phage KMI4 [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic

RECORD: Rec_0345885 VERIFIED: NO