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MYP_037085
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Basic Information
IsCT-a (Derived from IsCT-P)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
13 amino acids
C83H141N19O14
Standard
Sequence
ILKKIWKAIKKLF
Physicochemical Analysis
1629.13 Da
10.60
4.76
4.54
0.3658
0.41
0.89
0.11
-2.08
157.69
0.1538
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
558.41
2.08
20.0
19.0
59.0
116.0
3.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0265818 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'a' in sequence is Ala peptoid residue (N-methylglycine)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa (KCTC 1637)
2 μM
MIC
PMID16871429 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16871429/
RECORD: Rec_0310878 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'a' in sequence is Ala peptoid residue (N-methylglycine)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
MRSA (CCARM 3001)
2 μM
MIC
PMID16871429 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16871429/
RECORD: Rec_0343302 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'a' in sequence is Ala peptoid residue (N-methylglycine)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
400 μM
HC50
PMID16871429 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16871429/
RECORD: Rec_0348657 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'a' in sequence is Ala peptoid residue (N-methylglycine)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
MRSA (CCARM 3543)
1 μM
MIC
PMID16871429 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16871429/
RECORD: Rec_0407178 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
The 'a' in sequence is Ala peptoid residue (N-methylglycine)
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis (KCTC 1917)
1 μM
MIC
PMID16871429 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16871429/
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