Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC900H1426N252O244S7

DescriptionStandard

        AHEPLAHEPMLLLALTEVMANSAAFTYFTAGALRRNISSNMLPQRFPLQLRTKSLGVFSPKLQELYPDQPMELQLSARRQPLISCHPHALHGTLFGSAEAFVVLPNGTRAPAFLLHVDASVTGKPTITRNRLGGTVKLAGPAVPSRGSGAASPQVKRLETLLKFGLWLFGVPWANSECCPHPVP
    

Molecular Weight19904.95 Da

Isoelectric Point (pI)9.85

Net Charge (pH 7.0)7.39

Net Charge (pH 7.4) 6.78

Charge Density (pH 7.0) 0.0402

GRAVY Index0.03

Hydrophobic Moment 0.54

Boman Index0.11

Instability Index56.58

Aliphatic Index 91.79

Aromaticity 0.0707

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7750.12

LogP -89.10

H-bond Donors 266.0

H-bond Acceptors 265.0

Rotatable Bonds 627.0

Heavy Atoms 1403.0

Ring Count 41.0

Amide Bonds 196.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0258663 VERIFIED: NO

Provenance & Taxonomy

OrganismBrachypteracias leptosomus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria