Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length55 amino acids

Chemical FormulaC272H430N68O84S6

DescriptionStandard

        METEKYLQVVEDEEIEQLVGGAGPGWVETLTKDCPWNVPVACVTIMGQRICKKCY
    

Molecular Weight6189.12 Da

Isoelectric Point (pI)4.48

Net Charge (pH 7.0)-4.52

Net Charge (pH 7.4) -4.82

Charge Density (pH 7.0) -0.0822

GRAVY Index-0.14

Hydrophobic Moment 0.49

Boman Index0.08

Instability Index59.45

Aliphatic Index 83.09

Aromaticity 0.0727

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2435.35

LogP -19.29

H-bond Donors 85.0

H-bond Acceptors 86.0

Rotatable Bonds 203.0

Heavy Atoms 430.0

Ring Count 9.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0385329 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus thuringiensis subsp. kurstaki [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria

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