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MYP_037047
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Basic Information
WL2 (Derived from CP-1)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C102H172N26O23
Standard
Sequence
WLSKTAKKLWLSKTAKKL
Physicochemical Analysis
2130.62 Da
10.70
5.75
5.54
0.3197
-0.52
0.47
-0.13
26.88
97.78
0.1111
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
826.64
-4.17
31.0
29.0
75.0
151.0
4.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010047 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli UB1005
8 μM
MIC
PMID29266746 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29266746/
RECORD: Rec_0019320 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli UB1005
8 μM
MIC
PMID29266746 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29266746/
RECORD: Rec_0039062 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic
human red blood cells
PMID29266746 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29266746/
RECORD: Rec_0065339 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
The cell viability of IPEC-J2 cells induced by the control Melittin is 77
PMID29266746 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29266746/
RECORD: Rec_0093874 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Cytotoxic
The cell viability of IPEC-J2 cells induced by WL2 is 99
PMID29266746 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29266746/
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