Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length257 amino acids

Chemical FormulaC1321H1996N292O383S11

DescriptionStandard

        LCALCNIGYFALSTTLTVLMPIDDLAEIDYSLNSLPAVFQPFIDLDLKGIVYPAGNYSGPPYVAAPFTIPDQSDSMLYLAFSEYFFQTCSFAYYTAGAFNITIAEEVKSGKLFYLFFSFFLQTCSYFNISTEIFGSIIPEVAKYSVTPYPVMLKLMATEIPIISLEQDSFTAEIQGSMEVFAVLPDSTTHSLFTVNIAANTSIALNIFDQKLMGSLCLNRLQFSLTHSNVGFFEISLLENILSYILQTEVIPSANGK
    

Molecular Weight28448.42 Da

Isoelectric Point (pI)4.17

Net Charge (pH 7.0)-15.09

Net Charge (pH 7.4) -15.53

Charge Density (pH 7.0) -0.0587

GRAVY Index0.49

Hydrophobic Moment 0.55

Boman Index0.30

Instability Index46.11

Aliphatic Index 102.88

Aromaticity 0.1440

Extinction Coeff. Reduced 20860.00

Extinction Coeff. Oxidized 21110.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0386853 VERIFIED: NO

Provenance & Taxonomy

OrganismOceanites oceanicus (Wilson`s storm petrel) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria