Peptide Database

Peptide NameCecropin B

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length35 amino acids

Chemical FormulaC176H300N52O44S

DescriptionStandard

        RWKVFKKIEKMGRNIRDGIIKAGPAVEVLGSAKAL
    

Molecular Weight3880.65 Da

Isoelectric Point (pI)10.64

Net Charge (pH 7.0)5.76

Net Charge (pH 7.4) 5.54

Charge Density (pH 7.0) 0.1646

GRAVY Index-0.16

Hydrophobic Moment 0.89

Boman Index-0.05

Instability Index55.53

Aliphatic Index 103.14

Aromaticity 0.0571

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1576.76

LogP -11.41

H-bond Donors 56.0

H-bond Acceptors 51.0

Rotatable Bonds 137.0

Heavy Atoms 273.0

Ring Count 4.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0003460 VERIFIED: YES

Provenance & Taxonomy

OrganismSpodoptera exigua [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)