Peptide Database

Peptide NameMartentoxin II

Function Ontology

Annotation / Sequence feature ▸ Nuclear export signal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC171H268N50O53S6

DescriptionStandard

        FGLIDVKCFASSECWTACKKVTGSGQGKCQNNQCRCY
    

Molecular Weight4064.65 Da

Isoelectric Point (pI)8.65

Net Charge (pH 7.0)2.70

Net Charge (pH 7.4) 2.40

Charge Density (pH 7.0) 0.0730

GRAVY Index-0.31

Hydrophobic Moment 0.37

Boman Index-0.05

Instability Index30.16

Aliphatic Index 42.16

Aromaticity 0.1081

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1704.12

LogP -22.04

H-bond Donors 65.0

H-bond Acceptors 62.0

Rotatable Bonds 136.0

Heavy Atoms 280.0

Ring Count 5.0

Amide Bonds 41.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0252729 VERIFIED: NO

Provenance & Taxonomy

OrganismButhus martensii,Mesobuthus martensii [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-29; 14-34; 18-36

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0382480 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyPotassium channel inhibitor family

Tax ID34649; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-29; 14-34; 18-36

Bio-Activity Profile

Function

Toxin Venom Potassium channel inhibitor family Ion channel inhibitor Pathogenesis-associated Host defense