MYP_036946
Insulin-like growth factor I
Binding / Molecular interaction
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Binding activity
Hormonal / Endocrine
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Hormone peptide
Immunology
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Immune modulation
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Cytokine modulation
Neurological / Signaling
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Neuromodulation
Neurological / Signaling
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Neuropeptide activity
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Neuropeptide
Regulatory peptide
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Biological modulation
Regulatory peptide
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Biological regulation
Regulatory peptide
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Cell signaling / Growth factor signaling
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Growth factor activity
Therapeutic / Biomedical activity
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Regenerative medicine
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Tissue repair / Regeneration
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Bone regeneration
Standard
70 amino acids
C331H518N94O101S7
Standard
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
7654.68 Da
7.76
0.71
0.40
0.0101
-0.27
0.46
-0.05
67.24
60.00
0.1000
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
3126.93
-34.81
115.0
109.0
246.0
533.0
12.0
72.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0033160
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
IGF
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
I125 labeling
Bio-Activity Profile
Osteogenic
stimulates body protein and glucose metabolism and increases glomerular filtration rate and renal plasma flow
Radioimmunoassay and bi-exponential equation that describes a two-compartment model
Intravenous bolus administration in Rat, in vivo; 12180 s
RECORD: Rec_0033744
VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Insulin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone
Metabolic
RECORD: Rec_0038731
VERIFIED: YES
Provenance & Taxonomy
Panthera tigris altaica [Animal]
Insulin-like growth factor
74533
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-48; 18-61; 47-52
Bio-Activity Profile
Hormone
Endocrine
Neuropeptide
Neuromodulator
Metabolic regulation
Physiological regulation
Growth regulation
Development regulation
Receptor modulation
integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling
Experimental: 0.033±0.004 (t1/2 α) hours; /118.8 seconds; Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0047780
VERIFIED: YES
Provenance & Taxonomy
Sus scrofa [Animal]
Insulin-like growth factor
9823
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-48; 18-61; 47-52
Bio-Activity Profile
Hormone
Endocrine
Neuropeptide
Neuromodulator
Metabolic regulation
Physiological regulation
Growth regulation
Development regulation
Receptor modulation
integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling
Experimental: 0.033±0.004 (t1/2 α) hours; /118.8 seconds; Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0060150
VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
IGF
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Stmulates glycogen synthesis
Radioimmunoassay
Rat Serum, in vivo; 6000 s
Showing 5 records on this page · Page 2 of 11